发明名称 |
CD89 activation in therapy |
摘要 |
The invention relates to the use of CD89 activating molecules, in particular Fc alpha comprising molecules, and more particularly, IgA, for inducing apoptosis in neutrophils. Anti-CD89 antibodies can alternatively be used. The CD89 activation is beneficial in the treatment of various disorders associated with increases in neutrophils, such as autoimmune disorders, inflammatory disorders, NETosis, or cystic fibrosis. |
申请公布号 |
AU2011343392(A1) |
申请公布日期 |
2013.05.02 |
申请号 |
AU20110343392 |
申请日期 |
2011.12.14 |
申请人 |
CSL BEHRING AG;UNIVERSITAT BERN |
发明人 |
VON GUNTEN, STEPHAN;WEHRLI, MARC;ZURCHER, ADRIAN;MIESCHER, SYLVIA |
分类号 |
C07K16/28;A61K39/395;A61P37/00 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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