| 发明名称 |
Antibody drug conjugates (ADC) that bind to 191P4D12 proteins |
| 摘要 |
Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer. |
| 申请公布号 |
AU2011312417(A1) |
申请公布日期 |
2013.05.02 |
| 申请号 |
AU20110312417 |
申请日期 |
2011.09.29 |
| 申请人 |
AGENSYS, INC. |
发明人 |
SATPAEV, DAULET;MORRISON, ROBERT KENDALL;MORRISON, KAREN JANE MEYRICK;GUDAS, JEAN;JAKOBOVITS, AYA;TORGOV, MICHAEL;AN, ZILI |
| 分类号 |
C07K1/00;A61K39/00;A61K39/395 |
主分类号 |
C07K1/00 |
| 代理机构 |
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