发明名称 |
Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom |
摘要 |
A first aspect of the invention provides meningococcal outer membrane vesicles in which NHBA is over-expressed. A second aspect of the invention provides meningococcal outer membrane vesicles in which NadA is over-expressed. A third aspect of the invention provides a panel of bacterial strains, each member of which is isogenic except for a single gene which in each strain encodes a different variant of an antigen of interest. |
申请公布号 |
AU2011300418(A1) |
申请公布日期 |
2013.05.02 |
申请号 |
AU20110300418 |
申请日期 |
2011.09.09 |
申请人 |
NOVARTIS AG |
发明人 |
SERRUTO, DAVIDE;PIZZA, MARIAGRAZIA;DELANY, ISOBEL |
分类号 |
A61K39/095;C12N1/00 |
主分类号 |
A61K39/095 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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