The present invention relates generally to the field of crystallography. More particularly, the present invention provides crystalline forms of a complex between granulocyte macrophage-colony stimulating factor (GM-CSF) and its receptor (GM-CSFR). The present invention further provides methods for the design and selection of modulators of GM-CSF/GM-CSFR interaction and signaling as well as signaling of other cytokines.
申请公布号
AU2007314164(B2)
申请公布日期
2013.05.02
申请号
AU20070314164
申请日期
2007.11.01
申请人
ST. VINCENT'S INSTITUTE OF MEDICAL RESEARCH;CENTRAL ADELAIDE LOCAL HEALTH NETWORK INC OPERATING AS SA PATHOLOGY
发明人
HANSEN, GUIDO;LOPEZ, ANGEL FRANCISCO;PARKER, MICHAEL WILLIAM;MCKINSTRY, WILLIAM JOHN;HERCUS, TIMOTHY ROBERT
