发明名称 |
Naphthridine derivatives as PI3K inhibitors for the treatment of cancer and immune-inflammatory disease |
摘要 |
Compounds of formulae (I) and (II): or a pharmaceutically acceptable salt thereof, wherein: R1 is a nitrogen-containing 5 to 7-membered heteroaryl or heterocycle; R2 and R3 are each independently (LQ)mY, are described. The compounds are PI3K inhibitors and are useful for the treatment of cancer and immune-inflammatory diseases.
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申请公布号 |
US2013109688(A1) |
申请公布日期 |
2013.05.02 |
申请号 |
US201113643210 |
申请日期 |
2011.04.26 |
申请人 |
SHUTTLEWORTH STEPHEN JOSEPH;SILVA FRANCK ALEXANDRE;KARUS THERAPEUTICS LIMITED |
发明人 |
SHUTTLEWORTH STEPHEN JOSEPH;SILVA FRANCK ALEXANDRE |
分类号 |
C07D471/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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