| 摘要 |
The invention provides novel inhibitors of hedgehog signaling that are useful as a therapeutic agent for treating malignancies where the compounds have the general formula (I): where A, X, Y R1, R 2, R 3, R4, m and n are as described herein. |
| 申请人 |
GENENTECH, INC.;CURIS, INC. |
发明人 |
GUNZNER, JANET L.;SUTHERLIN, DANIEL P.;STANLEY, MARK S.;BAO, LIANG;CASTANEDO, GEORGETTE;LALONDE, REBECCA L.;WANG, SHUMEI;REYNOLDS, MARK E.;SAVAGE, SCOTT J.;MALESKY, KIMBERLY;DINA, MICHAEL S. |
