发明名称 NEPRILYSIN INHIBITORS
摘要 In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.
申请公布号 US2013109639(A1) 申请公布日期 2013.05.02
申请号 US201213666538 申请日期 2012.11.01
申请人 HUGHES ADAM D.;FENSTER ERIK;FLEURY MELISSA;GENDRON ROLAND 发明人 HUGHES ADAM D.;FENSTER ERIK;FLEURY MELISSA;GENDRON ROLAND
分类号 C07C235/74;A61K31/197;A61K31/22;A61K31/24;A61K31/265;A61K31/365;A61K31/7048;A61P9/04;A61P9/12;A61P13/12;C07C231/02;C07C241/02;C07C243/28;C07D317/40;C07D407/12 主分类号 C07C235/74
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