发明名称 BIOMARKER FOR SENSITIVITY TO ANTI-IGF1R THERAPY
摘要 <P>PROBLEM TO BE SOLVED: To provide, for example, methods for conveniently determining if a cancerous condition in a subject is responsive to an IGF1R inhibitor. <P>SOLUTION: The invention provides, for example, the methods for conveniently determining if a cancerous condition in a subject is responsive to an IGF1R inhibitor. The invention includes patient selection methods and methods of treatment. The invention is a method for selecting a subject with malignant or neoplastic cells for treatment with an IGF1R inhibitor comprising a step of evaluating sensitivity of the malignant or neoplastic cells to the inhibitor by the method for evaluating sensitivity discussed; wherein the subject is selected if the cells are determined to be sensitive. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013078341(A) 申请公布日期 2013.05.02
申请号 JP20130012872 申请日期 2013.01.28
申请人 MERCK SHARP & DOHME CORP 发明人 WANG YAN;WANG YAOLIN;LEVITAN DIANE;SEIDEL-DUGAN CYNTHIA;LIU MING;DING WEI
分类号 C12Q1/68;A61K31/436;A61K45/00;A61P35/00;A61P35/02;A61P43/00;C12N15/09;G01N33/53 主分类号 C12Q1/68
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