发明名称 |
TDP-43 SPECIFIC BINDING MOLECULES |
摘要 |
Provided are novel TDP-43 -specific binding molecules including polypeptides such as human antibodies, as well as fragments, derivatives and variants thereof. Also provided are methods related to these TDP-43 specific binding molecules. Assays, kits, and solid supports related to TDP-43 -specific binding molecules, including polypeptides such as, human antibodies are also disclosed. The TDP-43-specific binding molecule, antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for TDP-43 targeted immunotherapy and diagnosis, respectively. |
申请公布号 |
CA2853412(A1) |
申请公布日期 |
2013.05.02 |
申请号 |
CA20122853412 |
申请日期 |
2012.10.26 |
申请人 |
UNIVERSITY OF ZURICH;BIOGEN IDEC INTERNATIONAL NEUROSCIENCE GMBH |
发明人 |
ROGER, NITSCH;HOCK, CHRISTOPH;BARENCO MONTRASIO, MARIA GRAZIA;MONTRASIO, FABIO;GRIMM, JAN;BAERISWYL, JEAN-LUC;WEINREB, PAUL;QUINTERO-MONZON, OMAR;COOMARASWAMY, JANAKY |
分类号 |
C07K16/18 |
主分类号 |
C07K16/18 |
代理机构 |
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