发明名称 |
METHOD FOR MANUFACTURING OF QUINOLINE-3-CARBOXAMIDES |
摘要 |
A method for preparing a compound of formula (I) by reacting the appropriate alkyl ester and an aniline derivative, in a refluxing mixture containing an aliphatic solvent or a mixture of aliphatic solvents having a boiling point in the range of 68-191° C.; condensing vapors of the refluxing mixture; treating the condensed vapors with an alcohol scavenging agent or a mixture of alcohol scavenging agents; and returning the condensed vapors back to the reaction mixture.
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申请公布号 |
US2013109860(A1) |
申请公布日期 |
2013.05.02 |
申请号 |
US201113809233 |
申请日期 |
2011.07.07 |
申请人 |
BOCK LILLEMOR MARIA;HOLMBERG PAR HENNING;JANSSON KARL-ERIK;ACTIVE BIOTECH AB |
发明人 |
BOCK LILLEMOR MARIA;HOLMBERG PAR HENNING;JANSSON KARL-ERIK |
分类号 |
C07D215/56 |
主分类号 |
C07D215/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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