发明名称 |
Pyrazole aminopyrimidine derivatives as LRRK2 modulators |
摘要 |
PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS Abstract Compounds of the formula I or pharmaceutically acceptable salts thereof, wherein X, R1, R2, R3, R4 and R are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with LRRK2 receptor, such as Parkinson's disease. |
申请公布号 |
AU2013203083(A1) |
申请公布日期 |
2013.05.02 |
申请号 |
AU20130203083 |
申请日期 |
2013.04.09 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BAKER-GLENN, CHARLES;BURDICK, DANIEL JON;CHAMBERS, MARK;CHEN, HUIFEN;ESTRADA, ANTHONY;SWEENEY, ZACHARY KEVIN;CHAN, BRYAN K. |
分类号 |
C07D401/14;A61K31/506;A61P25/16;C07D403/12;C07D403/14;C07D405/14;C07D413/14 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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