Novel lipid formulations for nucleic acid delivery

摘要

H:/aar/Intenvoven/NRPortbl/DCC/AAR/5054850_ .DOC-8/04/2013 The present invention provides novel, stable lipid particles comprising one or more active agents or therapeutic agents, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles. More particularly, the present invention provides stable nucleic acid-lipid particles (SNALP) comprising a nucleic acid (such as one or more interfering RNA), methods of making the SNALP, ;and methods of delivering and/or administering the SNALP. 113b