<p>The present invention relates to an isolated polynucelotide encoding a polypeptide with protoilludene synthase activity and comprising a sequence selected from the group consisting of a) SEQ ID Nos. 1 or 14 of the attached sequence listing; b) a nucleic acid sequence complementary to SEQ ID Nos. 1 or 14; c) nucleic acid sequences which hybridize under stringent conditions to the nucleic acid sequences defined in a) and b) or their complementary strands, as well as to the polypeptide encoded by the isolated polynucleotide, as well as their uses for the production of melleolides.</p>
申请公布号
EP2415865(B1)
申请公布日期
2013.05.01
申请号
EP20110157878
申请日期
2010.08.02
申请人
FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
发明人
JENNEWEIN, STEFAN, DR.;ENGELS, BENEDIKT;GROTHE, TORSTEN, DR.;STADLER, MARC, DR.