发明名称 DEVICE AND METHOD FOR THE PRODUCTION OF RADIOCHEMICAL COMPOUNDS
摘要 The device comprises a reaction module (2), a dosing module, a supply module and a dispensing module, where the reaction module comprises a reaction vessel (3) with a closable opening by which substances required for producing a predetermined radiochemical compounds are introduced into the reaction vessel. The produced radiochemical compound is removed from the reaction vessel of the reaction module. The dosing module comprises a pipetting head (9), which is relatively moved to the supply and reaction modules and comprises a dosage unit (10a, 10b, 10c, 12). The device comprises a reaction module (2), a dosing module, a supply module and a dispensing module, where the reaction module comprises a reaction vessel (3) with a closable opening by which substances required for producing a predetermined radiochemical compounds are introduced into the reaction vessel. The produced radiochemical compound is removed from the reaction vessel of the reaction module. The dosing module comprises a pipetting head (9), which is relatively moved to the supply and reaction modules and comprises a dosage unit (10a, 10b, 10c, 12). A reservoir for preparing the respective radiochemical compound is formed in the supply module. The reaction vessel of the reaction module has an internal volume of 10 nl to 20.000 mu ml. The reaction module comprises a heating- and/or cooling device and/or microwave. The reaction vessel comprises a closure, which is opened when the substances required for producing the respective radiochemical compounds is introduced in the reaction vessel or a reaction mixture or a part of the reaction mixture is discharged from the reaction vessel. The opening is closed by the closure after determining a supply or removal of the substance. The dosage unit closes the opening when the substances required for producing the respective radiochemical compound are introduced into the reaction vessel or the reaction mixture or a portion of the reaction mixture is dissipated from the reaction vessel. The pipetting head is movable in the x-, y-direction or x-, y- and z-direction. The device comprises the dosage unit, which removes a powdery substance from the supply module to transport the reaction module and introduces powdery substance into the reaction vessel via the opening, and/or a further dosage unit that removes a liquid substance from the supply module to transport the reaction module and introduces liquid substance into the reaction vessel via the opening. The dosage unit comprises channels (23) for the supply and removal of liquid and gaseous substances from the reaction vessel. An independent claim is included for a method for producing radiochemical compounds using a device.
申请公布号 EP2585211(A2) 申请公布日期 2013.05.01
申请号 EP20110828159 申请日期 2011.06.20
申请人 ABX ADVANCED BIOCHEMICAL COMPOUNDS GMBH;GESIM GESELLSCHAFT FUER SILIZIUM-MIKROSYSTEME MBH 发明人 MUELLER, MARCO;HOWITZ, STEFFEN
分类号 B01J19/00;C07B59/00 主分类号 B01J19/00
代理机构 代理人
主权项
地址