SILODOSIN-CYCLODEXTRINE INCLUSION COMPLEX

摘要

The invention relates to a process for the preparation of a pharmaceutical with an inclusion compound of the active substance silodosin or a pharmaceutically acceptable salt thereof and a cyclodextrin, comprising the process step: a) silodosin or a pharmaceutically acceptable salt thereof is brought into contact with a cyclodextrin in the presence of a solvent, giving rise to a silodosin-cyclodextrin inclusion compound; b) the silodosin-cyclodextrin inclusion compound of step a) is mixed with one or more pharmaceutically acceptable additives; c) drying of the product of step a) and/or step b); and d) if appropriate, the dried mixture is optionally further processed with further pharmaceutically acceptable additives to give a unit dose form.