发明名称 |
PHARMACEUTICAL COMPOSITION HAVING IMPROVED SOLUBILITY |
摘要 |
It is desired to provide a pharmaceutical composition containing a compound represented by formula (I) or a pharmacologically acceptable salt thereof, or a solvate thereof, which exhibits an inhibitory effect on activated blood coagulation factor X (FXa), and is useful as an agent for preventing and/or treating thrombosis, wherein the pharmaceutical composition exhibits favorable dissolution properties. The present invention relates to a solid pharmaceutical composition containing a compound represented by formula (I) or a pharmacologically acceptable salt thereof, or a solvate thereof, wherein the content of the compound represented by formula (I) is 0.5% by weight or more and less than 15% by weight with respect to the total weight of the pharmaceutical composition. |
申请公布号 |
EP2444087(A4) |
申请公布日期 |
2013.05.01 |
申请号 |
EP20100789543 |
申请日期 |
2010.06.17 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
KAMADA, MAKOTO;KIDOKORO, MOTONORI;SEKIGUCHI, GAKU |
分类号 |
A61K31/444;A61K9/20;A61K9/32;A61K9/36;A61P7/02;C07D513/04 |
主分类号 |
A61K31/444 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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