发明名称 PHARMACEUTICAL COMPOSITION HAVING IMPROVED SOLUBILITY
摘要 It is desired to provide a pharmaceutical composition containing a compound represented by formula (I) or a pharmacologically acceptable salt thereof, or a solvate thereof, which exhibits an inhibitory effect on activated blood coagulation factor X (FXa), and is useful as an agent for preventing and/or treating thrombosis, wherein the pharmaceutical composition exhibits favorable dissolution properties. The present invention relates to a solid pharmaceutical composition containing a compound represented by formula (I) or a pharmacologically acceptable salt thereof, or a solvate thereof, wherein the content of the compound represented by formula (I) is 0.5% by weight or more and less than 15% by weight with respect to the total weight of the pharmaceutical composition.
申请公布号 EP2444087(A4) 申请公布日期 2013.05.01
申请号 EP20100789543 申请日期 2010.06.17
申请人 DAIICHI SANKYO COMPANY, LIMITED 发明人 KAMADA, MAKOTO;KIDOKORO, MOTONORI;SEKIGUCHI, GAKU
分类号 A61K31/444;A61K9/20;A61K9/32;A61K9/36;A61P7/02;C07D513/04 主分类号 A61K31/444
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