摘要 |
<p>In its many embodiments, the present invention provides -substituted pyridazinone compounds as glucan synthase inhibitors, methods of preparing such compounds, pharmaceutical including one or more of such compounds, methods of preparing pharmaceutical formulations including one or more such compounds or one or more such compounds along with other antifungal agents, and methods of treatment, prevention, inhibition, or amelioration of one or more fungal infections associated with glucan synthase using such compounds or pharmaceutical compositions.</p> |
申请人 |
MERCK SHARP & DOHME CORP.;ALBANY MOLECULAR RESEARCH, INC. |
发明人 |
TING, PAULINE, C.;ASLANIAN, ROBERT, G.;CAO, JAINHUA;KIM, DAVID, WON-SHIK;KUANG, RONGZE;ZHOU, GANG;HERR, ROBERT, JASON;ZYCH, ANDREW, JOHN;YANG, JINHAI;WU, HEPING;ZORN, NICOLAS |