发明名称 Derivatives of 3-(2,4-dihydroxyphenyl)-1,2,4-triazole useful in the treatment of cancer
摘要 Disclosed is a triazole derivative represented by the general formula (1) below or a pharmacologically acceptable salt thereof. Also disclosed are a prodrug of such a triazole derivative and an HSP90 inhibitor containing any one of them as an active constituent. (1) (In the formula, X represents a halogen atom, an optionally substituted alkyl group, an optionally substituted alkenyl group or the like; Y represents a mercapto group, a hydroxyl group, an optionally substituted sulfonyl group, an optionally substituted amino group or the like; and R represents an optionally substituted aryl or amino group or the like.)
申请公布号 EP1857446(B1) 申请公布日期 2013.05.01
申请号 EP20060715416 申请日期 2006.03.08
申请人 NIPPON KAYAKU KABUSHIKI KAISHA 发明人 KURAMOCHI, HIROSHI;NIITSUMA, SETSUKO;NAKAMURA, MASAHARU;SATO, YOSHITAKA;SAITO, SEIICHI;TOMURA, ARIHIRO;ICHIKAWA, YUH-ICHIRO;KASUGA, YOUSUKE
分类号 C07D249/12;A61K31/5377;A61P35/00;A61P43/00 主分类号 C07D249/12
代理机构 代理人
主权项
地址