发明名称 |
Derivatives of 3-(2,4-dihydroxyphenyl)-1,2,4-triazole useful in the treatment of cancer |
摘要 |
Disclosed is a triazole derivative represented by the general formula (1) below or a pharmacologically acceptable salt thereof. Also disclosed are a prodrug of such a triazole derivative and an HSP90 inhibitor containing any one of them as an active constituent. (1) (In the formula, X represents a halogen atom, an optionally substituted alkyl group, an optionally substituted alkenyl group or the like; Y represents a mercapto group, a hydroxyl group, an optionally substituted sulfonyl group, an optionally substituted amino group or the like; and R represents an optionally substituted aryl or amino group or the like.) |
申请公布号 |
EP1857446(B1) |
申请公布日期 |
2013.05.01 |
申请号 |
EP20060715416 |
申请日期 |
2006.03.08 |
申请人 |
NIPPON KAYAKU KABUSHIKI KAISHA |
发明人 |
KURAMOCHI, HIROSHI;NIITSUMA, SETSUKO;NAKAMURA, MASAHARU;SATO, YOSHITAKA;SAITO, SEIICHI;TOMURA, ARIHIRO;ICHIKAWA, YUH-ICHIRO;KASUGA, YOUSUKE |
分类号 |
C07D249/12;A61K31/5377;A61P35/00;A61P43/00 |
主分类号 |
C07D249/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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