发明名称 |
PEPTIDO INMUNOGENICO DEL GLUTEN Y SUS APLICACIONES. |
摘要 |
The invention relates to an immunogenic peptide of eight amino acids that is generated naturally in the intestine of celiac patients by means of the hydrolysis of ingested gluten. In addition, the invention relates to the use of the peptide, or antibodies generated against same, for the in vitro monitoring and/or diagnosis of celiac disease, as well as to the use of such antibodies for the detection of gluten in food. The invention further relates to the use of the aforementioned peptide as a therapeutic target for the development of compounds or compositions for use in the diagnosis, treatment and/or prevention of this pathological condition, as well as to the use of the peptide and the antibodies against same for the prevention and/or treatment of celiac disease.
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申请公布号 |
ES2402286(A1) |
申请公布日期 |
2013.04.30 |
申请号 |
ES20110031576 |
申请日期 |
2011.09.29 |
申请人 |
UNIVERSIDAD DE VALLADOLID |
发明人 |
BERNARDO ORDIZ, DAVID;GARROTE ADRADOS, JOSE ANTONIO;BLANCO QUIROS, ALFREDO RAMON;ARRANZ SANZ, EDUARDO;CEBOLLA RAMIREZ, ANGEL |
分类号 |
C07K7/06;A61K38/08;G01N33/68 |
主分类号 |
C07K7/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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