| 发明名称 |
Compounds that interact with glucokinase regulatory protein for the treatment of diabetes |
| 摘要 |
The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts thereof, that interact with glucokinase regulatory protein. In addition, the present invention relates to methods of treating type 2 diabetes, and other diseases and/or conditions where glucokinase regulatory protein is involved using the compounds, or pharmaceutically acceptable salts thereof, and pharmaceutical compositions that contain the compounds, or pharmaceutically acceptable salts thereof. |
| 申请公布号 |
US8431563(B2) |
申请公布日期 |
2013.04.30 |
| 申请号 |
US201113215914 |
申请日期 |
2011.08.23 |
| 申请人 |
ASHTON KATE;BARTBERGER MICHAEL DAVID;BO YUNXIN;BRYAN MARIAN C.;CROGHAN MICHAEL;FOTSCH CHRISTOPHER HAROLD;HALE CLARENCE HENDERSON;KUNZ ROXANNE KAY;LIU LONGBIN;NISHIMURA NOBUKO;NORMAN MARK H.;PENNINGTON LEWIS DALE;POON STEVE FONG;STEC MARKIAN MYROSLAW;ST. JEAN, JR. DAVID JOSEPH;TAMAYO NURIA A.;TEGLEY CHRISTOPHER MICHAEL;YANG KEVIN CHAO;AMGEN INC. |
发明人 |
ASHTON KATE;BARTBERGER MICHAEL DAVID;BO YUNXIN;BRYAN MARIAN C.;CROGHAN MICHAEL;FOTSCH CHRISTOPHER HAROLD;HALE CLARENCE HENDERSON;KUNZ ROXANNE KAY;LIU LONGBIN;NISHIMURA NOBUKO;NORMAN MARK H.;PENNINGTON LEWIS DALE;POON STEVE FONG;STEC MARKIAN MYROSLAW;ST. JEAN, JR. DAVID JOSEPH;TAMAYO NURIA A.;TEGLEY CHRISTOPHER MICHAEL;YANG KEVIN CHAO |
| 分类号 |
A61K31/497;A01N41/10;A01N41/12;A61K31/10;A61K31/105;A61K31/435;A61K31/445;A61K31/495;A61K31/4965;A61K31/50;A61K31/501;A61K31/535;A61K31/54;C07C315/00;C07C317/00;C07D211/54;C07D211/70;C07D211/82;C07D237/00;C07D239/00;C07D241/02;C07D265/36;C07D279/12;C07D295/00;C07D401/00;C07D403/00;C07D405/00;C07D409/00;C07D411/00;C07D413/00;C07D491/00;C07D495/00;C07D497/00;C07D498/02 |
主分类号 |
A61K31/497 |
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