HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF

摘要

THE PRESENT INVENTION PROVIDES A HETEROCYCLIC COMPOUND REPRESENTED BY GENERAL FORMULA (1): WHEREIN R� IS A GROUP R?-Z?-, ETC., Z? IS A LOWER ALKYLENE GROUP, ETC., AND R? IS A GROUP REPRESENTED BY GENERAL FORMULA; WHEREIN R�� IS A HYDROGEN ATOM, ETC., M IS AN INTEGER FROM 1 TO 5; R� IS A HYDROGEN ATOM: Y IS CH OR N: A? IS A HETEROCYCLIC RING SELECTED FROM THE GROUP CONSISTING OF INDOLEDIYL GROUPS, WHEREIN THE HETEROCYCLIC RING MAY HAVE AT LEAST ONE SUBSTITUENT: T IS A GROUP -CO-, ETC.: R� IS A HYDROGEN ATOM, ETC.: R? IS A LOWER ALKYL GROUP OPTIONALLY SUBSTITUTED BY ONE OR MORE HYDROXY GROUPS, ETC.: R� AND R?, TOGETHER WITH THE NITROGEN ATOM TO WHICH THEY BIND, MAY BIND TO EACH OTHER AND FORM A 5- TO 10-MEMBERED SATURATED HETEROCYCLIC RING, WHEREIN THE HETEROCYCLIC RING MAY HAVE AT LEAST ONE SUBSTITUENT. THE HETEROCYCLIC COMPOUND OF THE PRESENT INVENTION HAS EXCELLENT EFFECTS OF SUPPRESSING THE PRODUCTION OF COLLAGEN AND/OR TREATING TUMORS.