发明名称 Process for the preparation of halofenate
摘要 <p>The present invention provides a compounds the formula (IV): and methods for producing an &alpha;-(phenoxy)phenylacetic acid compound of the formula: wherein R1 is a member selected from the group consisting of: each R2 is a member independently selected from the group consisting of (C1-C4)alkyl, halo, (C1-C4)haloalkyl, amino, (C1-C4)aminoalkyl, amido, (C1-C4)amidoalkyl, (C1-C4)sulfonylalkyl, (C1-C4)sulfamylalkyl, (C1-C4)alkoxy, (C1-C4)heteroalkyl, carboxy and nitro; the subscript n is 1 when R1 has the formula (a) or (b) and 2 when R1 has the formula (c) or (d); the subscript m is an integer of from 0 to 3; * indicates a carbon which is enriched in one stereoisomeric configuration; and the wavy line indicates the point of attachment of R1; and compounds.</p>
申请公布号 IL190325(A) 申请公布日期 2013.04.30
申请号 IL20080190325 申请日期 2008.03.20
申请人 METABOLEX INC. 发明人
分类号 A61K;C07D 主分类号 A61K
代理机构 代理人
主权项
地址