发明名称 Verfahren zur Herstellung von Lincomycin-Hydrochlorid-Kristallen hoher Dichte
摘要 Polymorph II of lincomycin hydrochloride has a higher density than the normal polymorph I, is more suitable for encapsulating and has a characteristic X-ray diffraction pattern. It is obtained by adding acetone slowly with stirring to an aqueous solution of lincomycin hydrochloride at a temperature above 25 DEG C. Lincomycin hydrochloride polymorph I is prepared in Specification 976,765. A therapeutic composition in the form of a capsule contains lincomycin hydrochloride polymorph II.
申请公布号 DE1207551(B) 申请公布日期 1965.12.23
申请号 DE1964U010987 申请日期 1964.08.26
申请人 THE UPJOHN COMPANY 发明人 OVERLOOP DONALD RALPH VAN
分类号 C07H15/16 主分类号 C07H15/16
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