| 发明名称 |
METHOD OF DETECTING ATHEROSCLEROTIC PLAQUES WITH CHANGED METHABOLIC ACTIVITY |
| 摘要 |
FIELD: medicine.SUBSTANCE: invention relates to medicine and can be used for detection of atherosclerotic plaques with changed metabolic activity. For this purpose 5-aminolevulinic acid is introduced. After that fluorescence spectra in excitation within the range of wavelength 390-650 nm are measured. Sections with increased accumulation of 5-ALC-induced protoporphyrin are determined. Areas with peak of fluorescence within the range 670-680 nm are determined among said sections.EFFECT: possibility of detecting atherosclerotic plaques with changed metabolic activity is provided, which can be used in selection of tactics of preventive and therapeutic procedures.1 dwg, 1 ex |
| 申请公布号 |
RU2480143(C1) |
申请公布日期 |
2013.04.27 |
| 申请号 |
RU20120105448 |
申请日期 |
2012.02.17 |
| 申请人 |
FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE NAUKI INSTITUT OBSHCHEJ FIZIKI IM. A.M. PROKHOROVA ROSSIJSKOJ AKADEMII NAUK (IOF RAN);FEDERAL'NOE GOSUDARSTVENNOE UNITARNOE PREDPRIJATIE "GOSUDARSTVENNYJ NAUCHNYJ TSENTR "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT ORGANICHESKIKH POLUPRODUKTOV I KRASITELEJ" (FGUP "GNTS "NIOPIK");ZAKRYTOE AKTSIONERNOE OBSHCHESTVO "BIOSPEK" (ZAO "BIOSPEK") |
发明人 |
VASIL'CHENKO SERGEJ JUR'EVICH;LOSHCHENOV VIKTOR BORISOVICH;EFREMOVA JULIJA EVGEN'EVNA;TARARAK EHDUARD MIKHAJLOVICH;KUZ'MIN SERGEJ GEORGIEVICH;VOROZHTSOV GEORGIJ NIKOLAEVICH |
| 分类号 |
A61B5/00 |
主分类号 |
A61B5/00 |
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