| 摘要 |
FIELD: chemistry.SUBSTANCE: invention discloses a product of modification of sulphanilic acid, and specifically n-(1,5-dihydro-3-methyl-8-R-8-R-9-hydroxy-[1,3]dioxepino[5,6-c]pyridinyl-6-azo)phenylsulphonic acid and salt forms thereof of general formula I:, where R, Rare selected from a group comprising: a hydrogen atom, methyl, a linear or branched alkyl or Rand Rtogether form a spirocycloalkyl group. Compounds of formula (I) have antibacterial activity, are more efficient with respect to both gram-negative bacteria Proteus vulgaris, Pseudomonas aeroginosa and gram-positive bacteria Staphylococcus aureus, and can be used in medicine and veterinary.EFFECT: improved properties.1 cl, 1 tbl, 11 ex |
