发明名称 DERIVES HETEROCYCLIQUES UTILES DANS LE TRAITEMENT DES MALADIES NEURODEGENERATIVES
摘要 <p>The present invention relates to compounds of Formula (I) below, to their pharmaceutically acceptable salts and to their isomers or mixtures of isomers: HetAr&mdash;X&mdash;CHR1R2 (I) in which: -HetAr represents a group chosen from: &mdash;X represents a linear, saturated or unsaturated, hydrocarbon-based chain comprising from 8 to 22 carbon atoms, optionally interrupted by an &mdash;NH&mdash; or &mdash;NH&mdash;CO&mdash; group, &mdash;R1 represents a hydrogen atom or an &mdash;OH, &mdash;O(C1-C6)alkyl, &mdash;OCO((C1-C6)alkyl), &mdash;OSO2((C1-C6)alkyl) or &mdash;OSO3H group, and &mdash;R2 represents a hydrogen atom or a (C2-C6)alkynyl, (C2-C6)alkenyl or (C3-C6)cycloalkyl group. The present invention also relates to a process for preparing the compounds of Formula (I), and also to the use thereof, especially in the treatment of neurodegenerative diseases.</p>
申请公布号 FR2933977(B1) 申请公布日期 2013.04.26
申请号 FR20080054921 申请日期 2008.07.18
申请人 CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) 发明人 SCHMIDT FANNY;FIGADERE BRUNO;VOZARI RITA SYLVIA;CHAMPY PIERRE;FRANCK XAVIER
分类号 C07D239/94;A61K31/517;A61P25/16;A61P25/28 主分类号 C07D239/94
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