发明名称 COMPOUND HAVING DETRUSOR MUSCLE-CONTRACTING ACTIVITY AND URETHRAL SPHINCTER MUSCLE-RELAXING ACTIVITY
摘要 <p>Disclosed is a compound of formula I, such as 2-[(2-{ (1R,5R)-2-oxo-5-[(1E)-7,8,8-trifluoro-4-hydroxy-4-methyl-1,7-octadien-1-yl]cyclopentyl} ethyl)thio]-1,3-thiazole-4-carboxylic acid and 2-[(2-{ (1R,5R)-2-oxo-5-[(1E, 4S)-7,8,8-trifluoro-4-hydroxy-4-methyl-1,7-octadien-1-yl]cyclopentyl} ethyl)thio]-1,3-thiazole-4-carboxylic acid, which is useful as an agent for contracting the bladder detrusor and relaxing the urethral sphincter.</p>
申请公布号 NZ596960(A) 申请公布日期 2013.04.26
申请号 NZ20100596960 申请日期 2010.06.09
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 OHMOTO, KAZUYUKI;KINOSHITA, AKIHIRO;MATSUYA, HIDEKAZU;OKADA, HIROKI
分类号 A61P43/00;A61K31/426;A61K45/00;A61P13/02;A61P13/10;C07D277/20;C07D277/36;C07D277/56 主分类号 A61P43/00
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