发明名称 |
TASTE-MASKED PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION AND A PROCESS FOR THE PREPARATION THEREOF |
摘要 |
A pharmaceutical composition for oral administration, wherein taste of the pharmaceutically active ingredient is masked, prepared by wet granulation of a mixture of a pharmaceutically active ingredient, at least one compound selected from the group consisting of magnesium aluminometasilicate and calcium silicate, and a pharmacologically acceptable carrier, and a method of preparing the pharmaceutical composition. The oral pharmaceutical composition may be prepared without using a costly special manufacturing system or additive, have an off-taste masking effect on active ingredients, and exhibit an appropriate drug dissolution behavior in the body for manifestation of pharmaceutical effect. Also, the oral pharmaceutical composition is compatible with both a water-soluble active ingredient and a poorly water-soluble active ingredient, with high industrial applicability due to simple manufacturing processes and high economical efficiency and productivity. The oral pharmaceutical composition may be formulated in any of a variety of solid dosage forms with improved pharmaceutical characteristics. |
申请公布号 |
WO2013058496(A1) |
申请公布日期 |
2013.04.25 |
申请号 |
WO2012KR08230 |
申请日期 |
2012.10.11 |
申请人 |
DAEWOONG PHARMACEUTICAL CO., LTD. |
发明人 |
CHANG, HEE CHUL;PARK, SANG HAN;KANG, BOK KI |
分类号 |
A61K9/20;A61K9/48;A61K47/02 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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