RECOMBINANT VECTOR, RECOMBINANT YEAST CONTAINING THE VECTOR, AND MASS-PRODUCING METHOD OF GLUCOSE OXIDASE USING THE YEAST

摘要

The present invention relates to a method for mass-producing glucose oxidase using a recombinant vector and a recombinant yeast. More particularly, the present invention relates to a recombinant vector comprising a modified glucose oxidase gene, a recombinant yeast transformed with the recombinant vector, a recombinant yeast further comprising a bacterial hemoglobin gene, and a method for producing glucose oxidase using the recombinant yeast. The glucose oxidase produced by the above method can be used for the preparation of organic acid calcium, which is useful in the prevention or treatment of metabolic bone diseases including osteoporosis or arthritis.