发明名称 ANTAGONISTS OF TWEAK AND OF TWEAK RECEPTOR AND THEIR USE TO TREAT IMMUNOLOGICAL DISORDER
摘要 <P>PROBLEM TO BE SOLVED: To effectively and specifically block aspects of the development of GVHD. <P>SOLUTION: Reagents modify the activity of TWEAK, and the reagents are used as therapeutic agents for the treatment of an immunological disorder. There are provided methods for blocking the development or treating or reducing the severity or effects of an immunological disorder in an animal including administering a pharmaceutical composition which comprises a therapeutically effective amount of a TWEAK blocking agent and a pharmaceutically acceptable carrier. There is also provided the composition having the therapeutically effective amount of the TWEAK blocking agent and the pharmaceutically acceptable carrier. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013075916(A) 申请公布日期 2013.04.25
申请号 JP20130006243 申请日期 2013.01.17
申请人 BIOGEN IDEC MA INC 发明人 RENNERT PAUL
分类号 A61K45/00;A61K38/00;A61K38/17;A61K39/395;A61P7/00;A61P7/06;A61P13/12;A61P21/00;A61P21/04;A61P29/00;A61P31/00;A61P31/18;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K14/705;C07K16/24;C07K16/28 主分类号 A61K45/00
代理机构 代理人
主权项
地址