发明名称 |
A CLUSTER OF NEUTRALIZING ANTIBODIES TO HEPATITIS C VIRUS |
摘要 |
Compositions and methods are provided relating to human anti-HCV E2 monoclonal antibodies. The antibodies of the invention bind to a conserved region of HCV E2 protein, and neutralize HCV virus across multiple HCV genotypes. Embodiments of the invention include isolated antibodies and derivatives and fragments thereof, pharmaceutical formulations comprising one or more of the human anti-HCV monoclonal antibodies; and cell lines that produce these monoclonal antibodies. |
申请公布号 |
WO2013033319(A3) |
申请公布日期 |
2013.04.25 |
申请号 |
WO2012US53024 |
申请日期 |
2012.08.30 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY;FOUNG, STEVEN;KECK, ZHEN-YONG |
发明人 |
FOUNG, STEVEN;KECK, ZHEN-YONG |
分类号 |
A61K39/29;C07K16/10 |
主分类号 |
A61K39/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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