发明名称 |
SERINE PROTEASE DERIVATIVES AND USES IN THE PREVENTION OR THE TREATMENT OF BLOOD COAGULATION DISORDERS |
摘要 |
The present invention relates to chimeric derivatives of serine protease zymogen containing the activation peptide of factor X or a fragment thereof for improving the half-life of said derivatives. Preferably, said chimeric derivatives are protein C and factor X derivatives. The invention also relates to said derivatives for the prevention or treatment of blood coagulation disorders.
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申请公布号 |
US2013101570(A1) |
申请公布日期 |
2013.04.25 |
申请号 |
US201313732465 |
申请日期 |
2013.01.02 |
申请人 |
ET DE LA RECHERCHE MEDICALE (INSERM) INSTITUT NATIONAL DE LA SANTE;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICLAE (INSERM) |
发明人 |
CHRISTOPHE OLIVIER;DENIS CECILE;CHEREL GHISLAINE;GUEGUEN PAUL |
分类号 |
C12N9/50 |
主分类号 |
C12N9/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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