| 摘要 |
The present invention relates to a method of treating hyperalgesia in a subject, which involves administering to a subject an amount of a TRPV1 agonist compound that selectively inhibits hyperactive nociceptive neurons. The present invention also relates to a method of selectively inhibiting hyperactive nociceptive neurons. Also disclosed is a method for reducing the electrical activity of hypersensitive neurons sensitized to TRPV1. The present invention also relates to a method for identifying candidate compounds that selectively inhibit hyperactive nociceptive neurons. Also disclosed is a pharmaceutical composition.
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