CLOSED-CYCLE CONTINUOUS FLOW SEPARATORS, SYSTEMS AND METHODS FOR THE CONTINUOUS ISOLATION OF TARGET CELLS

摘要

Provided are closed-cycle continuous flow separator systems for isolating target cell populations, which comprises in operable connection, a binding area for binding a target cell to a binding particle; a first continuous flow centrifuge for separating target cell bound binding particles from non-target cells; a de-binding area for de-binding the target cell from the binding particle; and a second continuous flow centrifuge for separating the target cell from the binding particle.