发明名称 MAMMALIAN CELL SURFACE ANTIGEN COMPRISING STRUCTURAL MOTIF CHARACTERISTIC OF MEMBER OF TNF LIGAND FAMILY
摘要 <P>PROBLEM TO BE SOLVED: To provide purified genes encoding a T cell surface antigen derived from a mammal, reagents related to the purified genes including purified proteins, specific antibodies, and nucleic acids encoding the antigen. <P>SOLUTION: There are provided the purified genes encoding the T cell surface antigen derived from a mammal, the reagents related to the purified genes including purified proteins, the specific antibodies, and the nucleic acids encoding the antigen. Methods for using the reagents and diagnostic kits are also provided. There are also provided compositions for treating autoimmune diseases, inflammatory diseases, systemic lupus erythematosus (SLE) or Hashimoto's autoimmune thyroiditis in animals. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013074899(A) 申请公布日期 2013.04.25
申请号 JP20120284208 申请日期 2012.12.27
申请人 MERCK SHARP & DOHME CORP 发明人 GORMAN DANIEL M;MATTSON JEANINE D
分类号 C12N15/09;G01N33/53;A61K38/00;A61K39/395;A61K48/00;A61P29/00;A61P37/02;A61P37/06;C07K14/52;C07K14/705;C07K16/24;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12N15/12;C12P21/02 主分类号 C12N15/09
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