发明名称 |
AMINOPYRIMIDINE USEFUL AS KINASE INHIBITOR |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide aminopyrimidines useful as kinase inhibitors. <P>SOLUTION: The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing the compounds. These compounds and pharmaceutically acceptable compositions thereof are useful for inhibiting kinases in vitro, in vivo, and ex vivo. <P>COPYRIGHT: (C)2013,JPO&INPIT |
申请公布号 |
JP2013075904(A) |
申请公布日期 |
2013.04.25 |
申请号 |
JP20120276504 |
申请日期 |
2012.12.19 |
申请人 |
VERTEX PHARMACEUTICALS INC |
发明人 |
BINCH HALEY;MORTIMORE MICHAEL;FRAYSSE DAMIEN;RUTHERFORD ALISTAIR |
分类号 |
C07D401/14;A61K31/397;A61K31/506;A61K45/00;A61P35/00;A61P35/02;A61P43/00;C07D403/14 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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