发明名称 |
PHOTOLABILE LINKER FOR THE SYNTHESIS OF HYDROXAMIC ACIDS |
摘要 |
<p>The present invention relates to a photolabile hydroxamate linker based on the o - nitroveratryl group and its application for multistep solid-phase synthesis and controlled photolytic release of hydroxamic acids. The invention provides a method for producing a solid support comprising a hydroxylamine - functionalized photolabile linker, and the so produced hydroxylamine - functionalized photolabile solid support. The invention further provides a method for synthesizing a one-bead-one compound library of hydroxamic acid derivatives on a photolabile linker, as well as a method for screening a library of hydroxamic acid derivatives.</p> |
申请公布号 |
WO2013057186(A1) |
申请公布日期 |
2013.04.25 |
申请号 |
WO2012EP70648 |
申请日期 |
2012.10.18 |
申请人 |
DANMARKS TEKNISKE UNIVERSITET |
发明人 |
NIELSEN, THOMAS E.;QVORTRUP, KATRINE |
分类号 |
C40B40/04;C07C235/06;C07C237/22;C07C237/42;C07C259/06;C07C259/10;C40B30/04;C40B50/14;C40B80/00 |
主分类号 |
C40B40/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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