| 发明名称 |
HUMAN ANTIBODIES AND PROTEINS |
| 摘要 |
<p>The present invention provides composite antibody variable regions or fragments thereof, which show reduced immunogenicity. In particular, composite antibody variable regions for use in humans are provided, in particular variable regions which have been modified to remove one or more T-cell epitopes. Methods for generating such variable regions are also provided.</p> |
| 申请公布号 |
EP1844074(B1) |
申请公布日期 |
2013.04.24 |
| 申请号 |
EP20060709606 |
申请日期 |
2006.02.03 |
| 申请人 |
ANTITOPE LIMITED |
发明人 |
JONES, TIMOTHY DAVID;BAKER, MATTHEW PAUL |
| 分类号 |
C07K16/00;C07K14/18;C07K14/415;C07K14/815;C07K16/24;C07K16/28;C07K16/32;C07K16/42;C07K16/46;C07K19/00 |
主分类号 |
C07K16/00 |
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