发明名称 PYRANYL ARYL METHYL BENZOQUINAZOLINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS
摘要 The present invention is directed to pyranyl aryl methyl benzoquinazolinone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
申请公布号 ZA201201205(B) 申请公布日期 2013.04.24
申请号 ZA20120001205 申请日期 2012.02.17
申请人 MERCK SHARP & DOHME CORP 发明人 KUDUK SCOTT D;CHANG RONALD K;GRESHOCK THOMAS J
分类号 A01N;A61K 主分类号 A01N
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