发明名称 |
METHODS FOR THE PREPARATION OF INJECTABLE DEPOT COMPOSITIONS |
摘要 |
Injectable depot compositions, comprising a biocompatible polymer which is a polymer or copolymer based on lactic acid and/or lactic acid plus glycolic acid having a monomer ratio of lactic to glycolic acid in the range from 48:52 to 100:0, a water-miscible solvent having a dipole moment of about 3.7-4.5 D and a dielectric constant of between 30 and 50, and a drug, were found suitable for forming in-situ biodegradable implants which can evoke therapeutic drug plasma levels from the first day and for at least 14 days. |
申请公布号 |
EP2582395(A2) |
申请公布日期 |
2013.04.24 |
申请号 |
EP20110723441 |
申请日期 |
2011.05.31 |
申请人 |
LABORATORIOS FARMACEUTICOS ROVI, S.A. |
发明人 |
GUTIERRO ADURIZ, IBON;GOMEZ OCHOA, MARIA, TERESA |
分类号 |
A61K47/34 |
主分类号 |
A61K47/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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