摘要 |
<p>Provided is a controlled-release preparation administered orally once a day that exhibits an optimum pharmacological clinical effect, prepared in the form of a bilayered tablet, a dual tablet, or a multilayered tablet including an immediate-release layer containing aceclofenac, a water-soluble additive, an insoluble additive, a solubilizer, a disintegrating agent and a filler, and a slow-release layer containing aceclofenac, a slow-release base, a disintegrating agent, a binder, a filler, a fluidizer, a solubilizer, and a lubricant.</p> |
申请人 |
KOREA UNITED PHARM, INC. |
发明人 |
LEE, BEOM JIN;JUNG, WON-TAE;CHOI, YOUN WOONG;NAM, KYU YEOL;CHO, SANG-MIN;JANG, JAE SANG;CHOI, MIN-JI |