PREPARATION OF SUSPENSION AEROSOL FORMULATIONS

摘要

The present invention provides processes for preparing suspension aerosol
formulations, wherein the particles for inhalation are formed in situ during
the process of manufacturing the formulation. In one aspect of the invention,
a process for preparing a suspension aerosol formulation comprises the steps
of: (a) dissolving one or more medicaments in one or more solvents to form a
solution; and (b) mixing one or more propellants with the solution under
conditions effective to precipitate, entirely or partially, at least one of
the medicaments.