发明名称 |
Immunoconjugates with an intracellularly-cleavable linkage |
摘要 |
The invention relates to therapeutic conjugates with improved ability to target various cancer cells containing a targeting moiety and a therapeutic moiety. The targeting and therapeutic moieties are linked via an acid cleavable linkage that increases therapeutic efficacy of the immunoconjugate.
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申请公布号 |
US8425912(B2) |
申请公布日期 |
2013.04.23 |
申请号 |
US201213586281 |
申请日期 |
2012.08.15 |
申请人 |
GOVINDAN SERENGULAM V.;IMMUNOMEDICS, INC. |
发明人 |
GOVINDAN SERENGULAM V. |
分类号 |
A61K39/395;A61K47/48;A61P35/00;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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