发明名称 |
BONE MORPHOGENIC PROTEIN BINDING PEPTIDE |
摘要 |
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the overall osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.
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申请公布号 |
US2013095075(A1) |
申请公布日期 |
2013.04.18 |
申请号 |
US201213481648 |
申请日期 |
2012.05.25 |
申请人 |
MURRAY SAMUEL S.;BEHNAM KEYVAN;BROCHMAN-MURRAY ELSA J.;DEPARTMENT OF VETERANS AFFAIRS;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
MURRAY SAMUEL S.;BEHNAM KEYVAN;BROCHMAN-MURRAY ELSA J. |
分类号 |
C07K14/47;A61K35/32;A61K38/17;C07K14/51 |
主分类号 |
C07K14/47 |
代理机构 |
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