发明名称 |
METHOD FOR DIFFERENTIALLY QUANTIFYING NATURALLY PROCESSED HLA-RESTRICTED PEPTIDES FOR CANCER, AUTOIMMUNE AND INFECTIOUS DISEASES IMMUNOTHERAPY DEVELOPMENT |
摘要 |
The invention relates to a method for quantitatively identifying relevant HLA-bound peptide antigens from primary tissue specimens on a large scale without labeling approaches. This method can not only be used for the development of peptide vaccines, but is also highly valuable for a molecularly defined immunomonitoring and the identification of new antigens for any immunotherapeutic strategy in which HLA-restricted antigenic determinants function as targets, such as a variety of subunit vaccines or adoptive T-cell transfer approaches in cancer, or infectious and autoimmune diseases. |
申请公布号 |
US2013096016(A1) |
申请公布日期 |
2013.04.18 |
申请号 |
US201113640989 |
申请日期 |
2011.04.15 |
申请人 |
WEINSCHENK TONI;FRITSCHE JENS;IMMATICS BIOTECHNOLOGIES GMBH |
发明人 |
WEINSCHENK TONI;FRITSCHE JENS |
分类号 |
G01N33/569 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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