发明名称 |
QUINOLINE DERIVATIVES AND USES OF THE SAME |
摘要 |
Provided is a quinoline derivative of Chemical Formula (I): wherein, R1 is a substituted or unsubstituted phenyl group, R2 is a halogen, and R3 is a substituted or unsubstituted phenyl group, and one of the carbon atoms in the phenyl ring of the phenyl group is optionally substituted by a nitrogen atom (N). The quinoline derivative can efficiently inhibit cancer cell proliferation and can be used for treating cancer, especially for treating cancers related to the Janus kinase-signal transducers and activators of transcription (JAK-STAT) pathway and/or the mitogen-activated protein kinase (MAPK) pathway.
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申请公布号 |
US2013096157(A1) |
申请公布日期 |
2013.04.18 |
申请号 |
US201213366697 |
申请日期 |
2012.02.06 |
申请人 |
HWA KUO-YUAN;LEE YU-MAY;CHEN YEH-LONG;TZENG CHERNG-CHYI;CHO HSIN-YUAN;NATIONAL TAIPEI UNIVERSITY OF TECHNOLOGY |
发明人 |
HWA KUO-YUAN;LEE YU-MAY;CHEN YEH-LONG;TZENG CHERNG-CHYI;CHO HSIN-YUAN |
分类号 |
A61K31/47;A61P35/00;C07D215/233 |
主分类号 |
A61K31/47 |
代理机构 |
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