A THERAPEUTIC AND DIAGNOSTIC TARGET GENE IN ACUTE MYELOID LEUKEMIA
摘要
Methods are provided for treating a cancer in a subject comprising administering to the subject an agent which inhibits expression of an HLX gene in the subject, or an agent which inhibits activity of an expression product of the HLX gene, and also for diagnosing a subject as likely to develop a cancer comprising determining whether a stem cell obtained from the subject expresses a HLX gene at a level in excess of predetermined control level. Kits therefor are also provided.
申请公布号
WO2012151390(A3)
申请公布日期
2013.04.18
申请号
WO2012US36303
申请日期
2012.05.03
申请人
ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY;DANA-FARBER CANCER INSTITUTE, INC.;STEIDL, ULRICH, G.;MITSIADES, CONSTANTINE, S.