发明名称 USE OF LIPID CONJUGATE IN CYSTIC FIBROSIS AND APPLICATION OF THE SAME
摘要 <P>PROBLEM TO BE SOLVED: To treat cystic fibrosis and reduce symptoms associated therewith. <P>SOLUTION: There is provided a use of a compound represented by a structure of general formula [L-Z-Y ]n-X for manufacturing a medicine composition that treats cystic fibrosis and reduces the symptoms associated with the same. In the formula, L is lipid or phospholipid, Z is nothing or either one of ethanolamine, serine, inositol, choline, and glycerol, Y is nothing or either one of spacer groups in a longitudinal extent of 2 or 30 atoms, and X is pharmacologically acceptable monomer, dimer, oligomer, or polymer. Herein, X is glycosaminoglycan, n is an integer of 1 or 1,000, and either bond between L, Z, Y, and X is amido bond or ester bond. <P>COPYRIGHT: (C)2013,JPO&INPIT
申请公布号 JP2013067670(A) 申请公布日期 2013.04.18
申请号 JP20130011660 申请日期 2013.01.25
申请人 MORRIA BIOPHARMACEUTICALS;YISSUM RESEARCH DEVELOPMENT CO OF THE HEBREW UNIVOF JERUSALEM LTD;TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK 发明人 YEDGAR SAUL;PRINCE ALICE;YUVAL COHEN
分类号 A61K31/726;A61K31/727;A61K31/728;A61K47/48;A61P11/00;A61P43/00 主分类号 A61K31/726
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