| 发明名称 |
NOVEL HETEROCYCLIC COMPOUNDS AS ERK INHBITORS |
| 摘要 |
The present invention provides a compound of the Formula I: (Formular I should be inserted here) or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2 and R3 are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same. |
| 申请公布号 |
US2013096084(A1) |
申请公布日期 |
2013.04.18 |
| 申请号 |
US201113703250 |
申请日期 |
2011.06.22 |
| 申请人 |
DENG YONGQI;ZHU LIANG;SHIPPS, JR. GERALD W.;LO SIE-MUN;SUN BINYUAN;HUANG XIAOHUA;BIENSTOCK COREY;COOPER ALAN B.;GAO XIAOLEI;YAO XIN;ZHU HUGH Y.;KELLY JOSEPH M.;BOGA SOBHANA BABU;ALHASSAN ABDUL-BASIT;TAGAT JAYARAM R.;MANSOOR UMAR FARUK;WILSON KEVIN J.;O'BOYLE BRENDAN M.;DANIELS MATTHEW HERSH;SCHELL ADAM;SILIPHAIVANH PHIENG;FISCHER CHRISTIAN |
发明人 |
DENG YONGQI;ZHU LIANG;SHIPPS, JR. GERALD W.;LO SIE-MUN;SUN BINYUAN;HUANG XIAOHUA;BIENSTOCK COREY;COOPER ALAN B.;GAO XIAOLEI;YAO XIN;ZHU HUGH Y.;KELLY JOSEPH M.;BOGA SOBHANA BABU;ALHASSAN ABDUL-BASIT;TAGAT JAYARAM R.;MANSOOR UMAR FARUK;WILSON KEVIN J.;O'BOYLE BRENDAN M.;DANIELS MATTHEW HERSH;SCHELL ADAM;SILIPHAIVANH PHIENG;FISCHER CHRISTIAN |
| 分类号 |
C07D401/14;A61K31/454;A61K31/4545;A61K31/506;A61K31/5377;A61K31/55;A61K31/551;A61K31/695;A61K45/06;C07D401/12;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D471/04;C07F7/18 |
主分类号 |
C07D401/14 |
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