发明名称 |
STABLE OPHTHALMICAL COMPOSITION COMPRISING KETOTIFEN AND NAPHAZOLINE AND METHODS OF MAKING SAME |
摘要 |
<p>Stable compositions comprising ketotifen or a ketotifen salt and methods of preparing such compositions are provided. The pH of the compositions remains at less than about 5 during storage. The methods comprise preparing pharmaceutical compositions comprising ketotifen or a ketotifen salt, and adjusting their pH to less than 5, thus slowing the changes of the active ingredients.</p> |
申请公布号 |
EP2150234(B1) |
申请公布日期 |
2013.04.17 |
申请号 |
EP20080873888 |
申请日期 |
2008.03.19 |
申请人 |
BAUSCH & LOMB INCORPORATED |
发明人 |
BRYANT, ROY, W.;PARIHAR, RAVI;ROWE, THOMAS;CABALLA, SUSAN |
分类号 |
A61K9/08;A61K31/4164;A61K31/453 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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